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Mutational Analysis of the T4 Gp59 Helicase Loader Reveals Its Sites for Interaction with Helicase, Single-stranded Binding Protein, and DNA

Efficient DNA replication involves coordinated interactions among DNA polymerase, multiple factors, and the DNA. From bacteriophage T4 to eukaryotes, these factors include a helicase to unwind the DNA ahead of the replication fork, a single-stranded binding protein (SSB) to bind to the ssDNA on the...

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Detalhes bibliográficos
Main Authors: Dolezal, Darin, Jones, Charles E., Lai, Xiaoqin, Brister, J. Rodney, Mueser, Timothy C., Nossal, Nancy G., Hinton, Deborah M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365714/
https://ncbi.nlm.nih.gov/pubmed/22427673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332080
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