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Bacteriophage T4 Helicase Loader Protein gp59 Functions as Gatekeeper in Origin-dependent Replication in Vivo

Bacteriophage T4 initiates origin-dependent replication via an R-loop mechanism in vivo. During in vitro reactions, the phage-encoded gp59 stimulates loading of the replicative helicase, gp41, onto branched intermediates, including origin R-loops. However, although gp59 is essential for recombinatio...

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Bibliographic Details
Main Authors: Dudas, Kathleen C., Kreuzer, Kenneth N.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1361368/
https://ncbi.nlm.nih.gov/pubmed/15781450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M502351200
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