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α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions

α-Synuclein has a central role in Parkinson disease, but its physiological function and the mechanism leading to neuronal degeneration remain unknown. Because recent studies have highlighted a role for α-synuclein in regulating mitochondrial morphology and autophagic clearance, we investigated the e...

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Bibliografische gegevens
Hoofdauteurs: Calì, Tito, Ottolini, Denis, Negro, Alessandro, Brini, Marisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365710/
https://ncbi.nlm.nih.gov/pubmed/22453917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302794
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