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Plasminogen Is a Complement Inhibitor

Plasminogen is a 92-kDa single chain glycoprotein that circulates in plasma as a zymogen and when converted to proteolytically active plasmin dissolves preformed fibrin clots and extracellular matrix components. Here, we characterize the role of plasmin(ogen) in the complement cascade. Plasminogen b...

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Bibliografiske detaljer
Main Authors: Barthel, Diana, Schindler, Susann, Zipfel, Peter F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365705/
https://ncbi.nlm.nih.gov/pubmed/22451663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323287
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