Significance of Calcium Binding, Tyrosine Phosphorylation, and Lysine Trimethylation for the Essential Function of Calmodulin in Vertebrate Cells Analyzed in a Novel Gene Replacement System

Calmodulin (CaM) was shown to be essential for survival of lower eukaryotes by gene deletion experiments. So far, no CaM gene deletion was reported in higher eukaryotes. In vertebrates, CaM is expressed from several genes, which encode an identical protein, making it difficult to generate a model sy...

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Detalhes bibliográficos
Main Authors: Panina, Svetlana, Stephan, Alexander, la Cour, Jonas M., Jacobsen, Kivin, Kallerup, Line K., Bumbuleviciute, Rasita, Knudsen, Kristoffer V. K., Sánchez-González, Pablo, Villalobo, Antonio, Olesen, Uffe H., Berchtold, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365693/
https://ncbi.nlm.nih.gov/pubmed/22493455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339382
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