Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

OBJECTIVES: Interleukin-23 (IL-23) has emerged as a new therapeutic target for the treatment of inflammatory bowel disease (IBD). As biomarkers of disease state and treatment efficacy are becoming increasingly important in drug development, we sought to identify efficacy biomarkers for anti-IL-23 th...

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Autori principali: Cayatte, Corinne, Joyce-Shaikh, Barbara, Vega, Felix, Boniface, Katia, Grein, Jeffrey, Murphy, Erin, Blumenschein, Wendy M, Chen, Smiley, Malinao, Maria-Christina, Basham, Beth, Pierce, Robert H, Bowman, Edward P, McKenzie, Brent S, Elson, Charles O, Faubion, William A, Malefyt, Rene de Waal, Kastelein, Robert A, Cua, Daniel, McClanahan, Terrill K, Beaumont, Maribel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
Soggetti:
Inflammatory Bowel Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365674/
https://ncbi.nlm.nih.gov/pubmed/23238132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2012.2
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