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Synthesis of Enantioenriched γ-Quaternary Cycloheptenones Using a Combined Allylic Alkylation/Stork–Danheiser Approach: Preparation of Mono-, Bi-, and Tricyclic Systems

A general method for the synthesis of β-substituted and unsubstituted cycloheptenones bearing enantioenriched all-carbon γ-quaternary stereocenters is reported. Hydride or organometallic addition to a seven-membered ring vinylogous ester followed by finely tuned quenching parameters achieves elimina...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bennett, Nathan B., Hong, Allen Y., Harned, Andrew M., Stoltz, Brian M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365663/
https://ncbi.nlm.nih.gov/pubmed/22009489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ob06189e
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