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Adenosine-guanosine preferential photocleavage of DNA by azido-benzoyl- and diazocyclopenta-dienylcarbonyloxy derivatives of 9-aminoacridine.

The photoreactions of 9-[6-(4-azidobenzamido)hexylamino]acridine (AHA) and 9-[6-(2-diazocyclopentadienylcarbonyloxy)hexylamino]acridine (DHA) with double stranded DNA result in formation of single strand nicks and alkali labile sites (adducts) with an efficiency of 6 x 10(-3) nicks per AHA and 3 x 1...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Nielsen, P E, Jeppesen, C, Egholm, M, Buchardt, O
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 1988
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2836803/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.9.3877
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