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CD140a identifies a population of highly myelinogenic, migration-competent, and efficiently engrafting human oligodendrocyte progenitor cells

Experimental models of myelin disorders can be treated by the transplantation of oligodendrocyte progenitor cells (OPCs) into the affected brain or spinal cord. OPCs express gangliosides recognized by MAb A2B5, but this marker also identifies lineage-restricted astrocytes and immature neurons. To es...

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Библиографические подробности
Главные авторы: Sim, Fraser J., McClain, Crystal, Schanz, Steven, Protack, Tricia L., Windrem, Martha S., Goldman, Steven A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365580/
https://ncbi.nlm.nih.gov/pubmed/21947029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1972
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