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CD140a identifies a population of highly myelinogenic, migration-competent, and efficiently engrafting human oligodendrocyte progenitor cells

Experimental models of myelin disorders can be treated by the transplantation of oligodendrocyte progenitor cells (OPCs) into the affected brain or spinal cord. OPCs express gangliosides recognized by MAb A2B5, but this marker also identifies lineage-restricted astrocytes and immature neurons. To es...

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Bibliographic Details
Main Authors: Sim, Fraser J., McClain, Crystal, Schanz, Steven, Protack, Tricia L., Windrem, Martha S., Goldman, Steven A.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365580/
https://ncbi.nlm.nih.gov/pubmed/21947029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1972
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