Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome–associated proteins

Dysfunction of the basement membrane protein QBRICK provokes Fraser syndrome, which results in renal dysmorphogenesis, cryptophthalmos, syndactyly, and dystrophic epidermolysis bullosa through unknown mechanisms. Here, we show that integrin α8β1 binding to basement membranes was significantly impair...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kiyozumi, Daiji, Takeichi, Makiko, Nakano, Itsuko, Sato, Yuya, Fukuda, Tomohiko, Sekiguchi, Kiyotoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365501/
https://ncbi.nlm.nih.gov/pubmed/22613833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201203065
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge