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Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome–associated proteins
Dysfunction of the basement membrane protein QBRICK provokes Fraser syndrome, which results in renal dysmorphogenesis, cryptophthalmos, syndactyly, and dystrophic epidermolysis bullosa through unknown mechanisms. Here, we show that integrin α8β1 binding to basement membranes was significantly impair...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365501/ https://ncbi.nlm.nih.gov/pubmed/22613833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201203065 |
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