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Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome–associated proteins

Dysfunction of the basement membrane protein QBRICK provokes Fraser syndrome, which results in renal dysmorphogenesis, cryptophthalmos, syndactyly, and dystrophic epidermolysis bullosa through unknown mechanisms. Here, we show that integrin α8β1 binding to basement membranes was significantly impair...

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Bibliografische gegevens
Hoofdauteurs: Kiyozumi, Daiji, Takeichi, Makiko, Nakano, Itsuko, Sato, Yuya, Fukuda, Tomohiko, Sekiguchi, Kiyotoshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365501/
https://ncbi.nlm.nih.gov/pubmed/22613833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201203065
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