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Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome–associated proteins

Dysfunction of the basement membrane protein QBRICK provokes Fraser syndrome, which results in renal dysmorphogenesis, cryptophthalmos, syndactyly, and dystrophic epidermolysis bullosa through unknown mechanisms. Here, we show that integrin α8β1 binding to basement membranes was significantly impair...

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Bibliografski detalji
Glavni autori: Kiyozumi, Daiji, Takeichi, Makiko, Nakano, Itsuko, Sato, Yuya, Fukuda, Tomohiko, Sekiguchi, Kiyotoshi
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365501/
https://ncbi.nlm.nih.gov/pubmed/22613833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201203065
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