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The C-terminal tail domain of metavinculin, vinculin’s splice variant, severs actin filaments

Vinculin and its splice variant, metavinculin (MV), are key elements of multiple protein assemblies linking the extracellular matrix to the actin cytoskeleton. Vinculin is expressed ubiquitously, whereas MV is mainly expressed in smooth and cardiac muscle tissue. The only difference in amino acid se...

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Bibliographic Details
Main Authors: Janssen, Mandy E.W., Liu, HongJun, Volkmann, Niels, Hanein, Dorit
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365496/
https://ncbi.nlm.nih.gov/pubmed/22613835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111046
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