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Airway responsiveness depends on the diffusion rate of methacholine across the airway wall
During methacholine challenge tests of airway responsiveness, it is invariably assumed that the administered dose of agonist is accurately reflected in the dose that eventually reaches the airway smooth muscle (ASM). However, agonist must traverse a variety of tissue obstacles to reach the ASM, duri...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365406/ https://ncbi.nlm.nih.gov/pubmed/22383507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00703.2011 |
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