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Abrogated cryptic activation of lentiviral transfer vectors
Despite significant improvements in lentivirus (LV) vector-based gene therapy there are still several safety risks using LV vectors including the potential formation of replication-competent LV particles. To address this shortcoming, we constructed a novel and safer gene transfer system using modifi...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365281/ https://ncbi.nlm.nih.gov/pubmed/22666541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00438 |
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