High-throughput, high-fidelity HLA genotyping with deep sequencing

Human leukocyte antigen (HLA) genes are the most polymorphic in the human genome. They play a pivotal role in the immune response and have been implicated in numerous human pathologies, especially autoimmunity and infectious diseases. Despite their importance, however, they are rarely characterized...

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Detalhes bibliográficos
Main Authors: Wang, Chunlin, Krishnakumar, Sujatha, Wilhelmy, Julie, Babrzadeh, Farbod, Stepanyan, Lilit, Su, Laura F., Levinson, Douglas, Fernandez-Viña, Marcelo A., Davis, Ronald W., Davis, Mark M., Mindrinos, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365218/
https://ncbi.nlm.nih.gov/pubmed/22589303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206614109
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