Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation

Follicular T-helper (T(FH)) cells cooperate with GL7(+)CD95(+) germinal center (GC) B cells to induce antibody maturation. Herein, we identify the transcription factor IRF4 as a T-cell intrinsic precondition for T(FH) cell differentiation and GC formation. After immunization with protein or infectio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bollig, Nadine, Brüstle, Anne, Kellner, Kerstin, Ackermann, Waltraud, Abass, Elfadil, Raifer, Hartmann, Camara, Bärbel, Brendel, Cornelia, Giel, Gavin, Bothur, Evita, Huber, Magdalena, Paul, Christoph, Elli, Alexandra, Kroczek, Richard A., Nurieva, Roza, Dong, Chen, Jacob, Ralf, Mak, Tak W., Lohoff, Michael
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2012
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365194/
https://ncbi.nlm.nih.gov/pubmed/22552227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205834109
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