HIV Delays IFN-α Production from Human Plasmacytoid Dendritic Cells and Is Associated with SYK Phosphorylation

Plasmacytoid dendritic cells (pDC) are the major producers of type I interferons (IFNs) in humans and rapidly produce IFN-α in response to virus exposure. Although HIV infection is associated with pDC activation, it is unclear why the innate immune response is unable to effectively control viral rep...

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Detalhes bibliográficos
Main Authors: Lo, Calvin C., Schwartz, Jordan A., Johnson, Dylan J., Yu, Monica, Aidarus, Nasra, Mujib, Shariq, Benko, Erika, Hyrcza, Martin, Kovacs, Colin, Ostrowski, Mario A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365039/
https://ncbi.nlm.nih.gov/pubmed/22693567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037052
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