Human Stanniocalcin-1 Suppresses Angiotensin II-Induced Superoxide Generation in Cardiomyocytes through UCP3-Mediated Anti-Oxidant Pathway

RATIONALE: We have previously shown increased cardiac stanniocalcin-1 (STC1) in patients with idiopathic dilated cardiomyopathy. STC1 localizes to the inner mitochondrial membrane and transgenic over-expression of STC1 is associated with increased energy utilization. OBJECTIVE: We examined the hypot...

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Detalhes bibliográficos
Main Authors: Liu, Dajun, Huang, Luping, Wang, Yanlin, Wang, Wei, Wehrens, Xander H.T., Belousova, Tatiana, Abdelrahim, Maen, DiMattia, Gabriel, Sheikh-Hamad, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365029/
https://ncbi.nlm.nih.gov/pubmed/22693564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036994
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