The App-Runx1 Region Is Critical for Birth Defects and Electrocardiographic Dysfunctions Observed in a Down Syndrome Mouse Model

Down syndrome (DS) leads to complex phenotypes and is the main genetic cause of birth defects and heart diseases. The Ts65Dn DS mouse model is trisomic for the distal part of mouse chromosome 16 and displays similar features with post-natal lethality and cardiovascular defects. In order to better un...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Raveau, Matthieu, Lignon, Jacques M., Nalesso, Valérie, Duchon, Arnaud, Groner, Yoram, Sharp, Andrew J., Dembele, Doulaye, Brault, Véronique, Hérault, Yann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364940/
https://ncbi.nlm.nih.gov/pubmed/22693452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002724
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados