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Allelic Variation and Differential Expression of the mSIN3A Histone Deacetylase Complex Gene Arid4b Promote Mammary Tumor Growth and Metastasis

Accumulating evidence suggests that breast cancer metastatic progression is modified by germline polymorphism, although specific modifier genes have remained largely undefined. In the current study, we employ the MMTV-PyMT transgenic mouse model and the AKXD panel of recombinant inbred mice to ident...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Winter, Scott F., Lukes, Luanne, Walker, Renard C., Welch, Danny R., Hunter, Kent W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364935/
https://ncbi.nlm.nih.gov/pubmed/22693453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002735
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