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Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1

BACKGROUND: Tra1 is an essential protein in Saccharomyces cerevisiae. It was first identified in the SAGA and NuA4 complexes, both with functions in multiple aspects of gene regulation and DNA repair, and recently found in the ASTRA complex. Tra1 belongs to the PIKK family of proteins with a C-termi...

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Autors principals: Kvas, Stephanie, Gloor, Gregory B, Brandl, Christopher J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364908/
https://ncbi.nlm.nih.gov/pubmed/22439631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-13-19
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