Synthetic Lethal Screen Identifies NF-κB as a Target for Combination Therapy with Topotecan for patients with Neuroblastoma

BACKGROUND: Despite aggressive multimodal treatments the overall survival of patients with high-risk neuroblastoma remains poor. The aim of this study was to identify novel combination chemotherapy to improve survival rate in patients with high-risk neuroblastoma. METHODS: We took a synthetic lethal...

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Main Authors: Tsang, Patricia S, Cheuk, Adam T, Chen, Qing-Rong, Song, Young K, Badgett, Thomas C, Wei, Jun S, Khan, Javed
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364855/
https://ncbi.nlm.nih.gov/pubmed/22436457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-101
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