Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease

Background. Paraoxonase 1 (PON1) enzymatic activity has been consistently predictive of cardiovascular disease, while the genotypes at the four functional polymorphisms at PON1 have not. The goal of this study was to identify additional variation at the PON gene cluster that improved prediction of P...

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Autori principali: Kim, Daniel S., Burt, Amber A., Ranchalis, Jane E., Richter, Rebecca J., Marshall, Julieann K., Eintracht, Jason F., Rosenthal, Elisabeth A., Furlong, Clement E., Jarvik, Gail P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364586/
https://ncbi.nlm.nih.gov/pubmed/22685667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/476316
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