Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease

Background. Paraoxonase 1 (PON1) enzymatic activity has been consistently predictive of cardiovascular disease, while the genotypes at the four functional polymorphisms at PON1 have not. The goal of this study was to identify additional variation at the PON gene cluster that improved prediction of P...

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Detalhes bibliográficos
Main Authors: Kim, Daniel S., Burt, Amber A., Ranchalis, Jane E., Richter, Rebecca J., Marshall, Julieann K., Eintracht, Jason F., Rosenthal, Elisabeth A., Furlong, Clement E., Jarvik, Gail P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364586/
https://ncbi.nlm.nih.gov/pubmed/22685667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/476316
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