Preformulation Study of NSC-726796

A stability-indicating high-performance liquid chromatography method to quantify 2-(2,4-difluorophenyl)-4,5,6,7-tetrafluoroisoindoline-1,3-dione (NSC-726796) and its three main degradation products was developed. This method was used to investigate its degradation kinetics and mechanism. The reactio...

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Autori principali: Guo, Duoli, Cain, James P., O’Connell, Sean, Gardner, Erin R., Pisle, Steven, Figg, William D., Tabibi, S. Esmail, Yalkowsky, Samuel H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364376/
https://ncbi.nlm.nih.gov/pubmed/22552929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9784-5
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