Abnormal Wnt and PI3Kinase Signaling in the Malformed Intestine of lama5 Deficient Mice

Laminins are major constituents of basement membranes and are essential for tissue homeostasis. Laminin-511 is highly expressed in the intestine and its absence causes severe malformation of the intestine and embryonic lethality. To understand the mechanistic role of laminin-511 in tissue homeostasi...

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Autors principals: Ritié, Léa, Spenlé, Caroline, Lacroute, Joël, Bolcato-Bellemin, Anne-Laure, Lefebvre, Olivier, Bole-Feysot, Christine, Jost, Bernard, Klein, Annick, Arnold, Christiane, Kedinger, Michèle, Bagnard, Dominique, Orend, Gertraud, Simon-Assmann, Patricia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364287/
https://ncbi.nlm.nih.gov/pubmed/22666383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037710
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