Mutations in Lama1 Disrupt Retinal Vascular Development and Inner Limiting Membrane Formation

The Neuromutagenesis Facility at the Jackson Laboratory generated a mouse model of retinal vasculopathy, nmf223, which is characterized clinically by vitreal fibroplasia and vessel tortuosity. nmf223 homozygotes also have reduced electroretinogram responses, which are coupled histologically with a t...

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Detalhes bibliográficos
Main Authors: Edwards, Malia M., Mammadova-Bach, Elmina, Alpy, Fabien, Klein, Annick, Hicks, Wanda L., Roux, Michel, Simon-Assmann, Patricia, Smith, Richard S., Orend, Gertraud, Wu, Jiang, Peachey, Neal S., Naggert, Jürgen K., Lefebvre, Olivier, Nishina, Patsy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844215/
https://ncbi.nlm.nih.gov/pubmed/20048158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069575
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