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APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration

Cell migration occurs by activation of complex regulatory pathways that are spatially and temporally integrated in response to extracellular cues. Binding of adenomatous polyposis coli (APC) to the microtubule plus ends in polarized cells is regulated by glycogen synthase kinase 3β (GSK-3β). This ev...

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Detalhes bibliográficos
Main Authors: Ekman, Maria, Mu, Yabing, Lee, So Young, Edlund, Sofia, Kozakai, Takaharu, Thakur, Noopur, Tran, Hoanh, Qian, Jiang, Groeden, Joanna, Heldin, Carl-Henrik, Landström, Maréne
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364175/
https://ncbi.nlm.nih.gov/pubmed/22496417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-12-1000
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