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Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications

BACKGROUND: Cervical cancer represents the third most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths in women worldwide. Natural killer (NK) cells play an important role in the defense against viruses, intracellular bacteria and tumors. NKG2D, an activating receptor...

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Main Authors: Jimenez-Perez, Miriam I, Jave-Suarez, Luis F, Ortiz-Lazareno, Pablo C, Bravo-Cuellar, Alejandro, Gonzalez-Ramella, Oscar, Aguilar-Lemarroy, Adriana, Hernandez-Flores, Georgina, Pereira-Suarez, Ana L, Daneri-Navarro, Adrian, del Toro-Arreola, Susana
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364150/
https://ncbi.nlm.nih.gov/pubmed/22316211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-7
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