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Role of the actin-binding protein profilin1 in radial migration and glial cell adhesion of granule neurons in the cerebellum

Profilins are small G-actin-binding proteins essential for cytoskeletal dynamics. Of the four mammalian profilin isoforms, profilin1 shows a broad expression pattern, profilin2 is abundant in the brain, and profilin3 and profilin4 are restricted to the testis. In vitro studies on cancer and epitheli...

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Main Authors: Rust, Marco B., Kullmann, Jan A., Witke, Walter
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364132/
https://ncbi.nlm.nih.gov/pubmed/22647936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.19845
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