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Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons

Cerebellar granule neurons (CGNs) exploit Bergmann glia (BG) fibres for radial migration, and cell–cell contacts have a pivotal role in this process. Nevertheless, little is known about the mechanisms that control CGN–BG interaction. Here we demonstrate that the actin-binding protein profilin1 is es...

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Bibliografske podrobnosti
Main Authors: Kullmann, Jan A, Neumeyer, Alexander, Gurniak, Christine B, Friauf, Eckhard, Witke, Walter, Rust, Marco B
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246249/
https://ncbi.nlm.nih.gov/pubmed/22081137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.211
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