S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E–Null Mice by Activating an Osteogenic Gene Regulatory Program

OBJECTIVE: The proinflammatory cytokine S100A12 is associated with coronary atherosclerotic plaque rupture. We previously generated transgenic mice with vascular smooth muscle–targeted expression of human S100A12 and found that these mice developed aortic aneurysmal dilation of the thoracic aorta. I...

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Detaylı Bibliyografya
Asıl Yazarlar: Hofmann Bowman, Marion A., Gawdzik, Joseph, Bukhari, Usama, Husain, Aliya N., Toth, Peter T., Kim, Gene, Earley, Judy, McNally, Elizabeth M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364048/
https://ncbi.nlm.nih.gov/pubmed/20966394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.217745
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