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Vascular Remodeling and Arterial Calcification Are Directly Mediated by S100A12 (EN-RAGE) in Chronic Kidney Disease

BACKGROUND: The proinflammatory cytokine S100A12 (also known as EN-RAGE) is associated with cardiovascular morbidity and mortality in hemodialysis patients. In the cur- rent study, we tested the hypothesis that S100A12 expressed in vascular smooth muscle in nonatherosclerosis-prone C57BL/6J mice on...

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Detalhes bibliográficos
Main Authors: Gawdzik, Joseph, Mathew, Liby, Kim, Gene, Puri, Tipu S., Hofmann Bowman, Marion A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064943/
https://ncbi.nlm.nih.gov/pubmed/21372560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324693
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