Lovastatin regulates brain spontaneous low-frequency brain activity in Neurofibromatosis type 1

In the Neurofibromatosis type 1 (NF1) mouse model, lovastatin, used clinically for hypercholesterolemia, improves cognitive dysfunction. While such impairment has been studied in NF1, the neural substrates remain unclear. The aim of this imaging add-on to a phase-1 open-label trial was to examine th...

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Main Authors: Chabernaud, Camille, Mennes, Maarten, Kardel, Peter G., Gaillard, William D., Kalbfleisch, M. Layne, VanMeter, John W., Packer, Roger J., Milham, Michael P., Castellanos, Francisco X., Acosta, Maria T.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3363969/
https://ncbi.nlm.nih.gov/pubmed/22433254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.03.009
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