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Lovastatin regulates brain spontaneous low-frequency brain activity in Neurofibromatosis type 1
In the Neurofibromatosis type 1 (NF1) mouse model, lovastatin, used clinically for hypercholesterolemia, improves cognitive dysfunction. While such impairment has been studied in NF1, the neural substrates remain unclear. The aim of this imaging add-on to a phase-1 open-label trial was to examine th...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3363969/ https://ncbi.nlm.nih.gov/pubmed/22433254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.03.009 |
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