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Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats

RATIONALE: Animal models of tobacco addiction rely on administration of nicotine alone or nicotine combined with isolated constituents. Models using tobacco extracts derived from tobacco products and containing a range of tobacco constituents might more accurately simulate tobacco exposure in humans...

詳細記述

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書誌詳細
主要な著者: Harris, Andrew C., Stepanov, Irina, Pentel, Paul R., LeSage, Mark G.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3363290/
https://ncbi.nlm.nih.gov/pubmed/21960181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2514-y
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