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Novobiocin induces positive supercoiling of small plasmids from halophilic archaebacteria in vivo.
The halophilic archaebacterium Halobacterium strain GRB harbours a multicopy plasmid of 1.7 kb which is negatively supercoiled. After addition of novobiocin to culture medium all 1.7 kb plasmid molecules become positively supercoiled. Positive supercoiling occurs at the same dose of novobiocin inhib...
保存先:
| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
1988
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| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3347494/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.4.1379 |
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