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Novobiocin induces positive supercoiling of small plasmids from halophilic archaebacteria in vivo.
The halophilic archaebacterium Halobacterium strain GRB harbours a multicopy plasmid of 1.7 kb which is negatively supercoiled. After addition of novobiocin to culture medium all 1.7 kb plasmid molecules become positively supercoiled. Positive supercoiling occurs at the same dose of novobiocin inhib...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1988
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3347494/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.4.1379 |
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