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Effects of the antitumor drug VP16 (etoposide) on the archaebacterial Halobacterium GRB 1.7 kb plasmid in vivo.

The topoprofile of 1.7 kb plasmids from the archaebacterium Halobacterium GRB was analysed from cells growing with or without VP16 (etoposide). This drug interferes with the breakage-reunion reaction of eukaryotic DNA topoisomerase II by inhibiting the ligase activity of this enzyme. Addition of VP1...

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Detaylı Bibliyografya
Asıl Yazarlar: Sioud, M, Forterre, P, de Recondo, A M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1987
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC306355/
https://ncbi.nlm.nih.gov/pubmed/3671082
Etiketler: Etiketle
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