Behavioral Effects and Central Nervous System Levels of the Broadly Available κ-Agonist Hallucinogen Salvinorin A Are Affected by P-Glycoprotein Modulation In Vivo

Active blood-brain barrier mechanisms, such as the major efflux transporter P-glycoprotein (mdr1), modulate the in vivo/central nervous system (CNS) effects of many pharmacological agents, whether they are used for nonmedical reasons or in pharmacotherapy. The powerful, widely available hallucinogen...

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Detaylı Bibliyografya
Asıl Yazarlar: Butelman, Eduardo R., Caspers, Michael, Lovell, Kimberly M., Kreek, Mary Jeanne, Prisinzano, Thomas E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2012
Konular:
Behavioral Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362888/
https://ncbi.nlm.nih.gov/pubmed/22434677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.193227
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