Characterization of the Antigen Specificity of T-Cell Clones from Piperacillin-Hypersensitive Patients with Cystic Fibrosis

β-Lactam antibiotics provide the cornerstone of treatment and reduce the rate of decline in lung function in patients with cystic fibrosis, but their use is limited by a high frequency of delayed-type allergic reactions. The objective of this study was to use cloned T-cells expressing a single T-cel...

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Hauptverfasser: El-Ghaiesh, Sabah, Monshi, Manal M., Whitaker, Paul, Jenkins, Rosalind, Meng, Xiaoli, Farrell, John, Elsheikh, Ayman, Peckham, Daniel, French, Neil, Pirmohamed, Munir, Park, B. Kevin, Naisbitt, Dean J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2012
Schlagworte:
Toxicology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362878/
https://ncbi.nlm.nih.gov/pubmed/22371438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.190900
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