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Differential Transcriptional Programming of Class-Specific B Cell Memory by T-bet and RORα

Antibody class defines function in B cell immunity, but how class is propagated into B cell memory remains poorly understood. Here, we demonstrate that memory B cell subsets unexpectedly diverge across antibody class through the differential impact of major transcriptional regulators. Conditional ge...

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Hlavní autoři: Wang, Nathaniel S., McHeyzer-Williams, Louise J., Okitsu, Shinji L., Burris, Thomas P., Reiner, Steven L., McHeyzer-Williams, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362691/
https://ncbi.nlm.nih.gov/pubmed/22561605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2294
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