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Differential Transcriptional Programming of Class-Specific B Cell Memory by T-bet and RORα
Antibody class defines function in B cell immunity, but how class is propagated into B cell memory remains poorly understood. Here, we demonstrate that memory B cell subsets unexpectedly diverge across antibody class through the differential impact of major transcriptional regulators. Conditional ge...
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Principais autores: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362691/ https://ncbi.nlm.nih.gov/pubmed/22561605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2294 |
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