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A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex
Aurora B kinase forms the enzymatic core of the Chromosomal Passenger Complex (CPC) and is a master regulator of mitosis. Understanding the regulation of Aurora B is critical to illuminate its role in mitosis. INCENP, Survivin and Borealin have all been known to promote Aurora B activation. In this...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362669/ https://ncbi.nlm.nih.gov/pubmed/22560880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.04.014 |
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