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A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex

Aurora B kinase forms the enzymatic core of the Chromosomal Passenger Complex (CPC) and is a master regulator of mitosis. Understanding the regulation of Aurora B is critical to illuminate its role in mitosis. INCENP, Survivin and Borealin have all been known to promote Aurora B activation. In this...

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Detalhes bibliográficos
Main Authors: Iyer, Jyoti, Tsai, Ming-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362669/
https://ncbi.nlm.nih.gov/pubmed/22560880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.04.014
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