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ZyFISH: A Simple, Rapid and Reliable Zygosity Assay for Transgenic Mice
Microinjection of DNA constructs into fertilized mouse oocytes typically results in random transgene integration at a single genomic locus. The resulting transgenic founders can be used to establish hemizygous transgenic mouse lines. However, practical and experimental reasons often require that suc...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362593/ https://ncbi.nlm.nih.gov/pubmed/22666404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037881 |
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