Targeting Melanoma Metastasis and Immunosuppression with a New Mode of Melanoma Inhibitory Activity (MIA) Protein Inhibition

Melanoma is the most aggressive form of skin cancer, with fast progression and early dissemination mediated by the melanoma inhibitory activity (MIA) protein. Here, we discovered that dimerization of MIA is required for functional activity through mutagenesis of MIA which showed the correlation betw...

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Main Authors: Schmidt, Jennifer, Riechers, Alexander, Stoll, Raphael, Amann, Thomas, Fink, Florian, Spruss, Thilo, Gronwald, Wolfram, König, Burkhard, Hellerbrand, Claus, Bosserhoff, Anja Katrin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362532/
https://ncbi.nlm.nih.gov/pubmed/22666418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037941
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