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Glutathione/thioredoxin systems modulate mitochondrial H(2)O(2) emission: An experimental-computational study

The net emission of hydrogen peroxide (H(2)O(2)) from mitochondria results from the balance between reactive oxygen species (ROS) continuously generated in the respiratory chain and ROS scavenging. The relative contribution of the two major antioxidant systems in the mitochondrial matrix, glutathion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aon, Miguel Antonio, Stanley, Brian Alan, Sivakumaran, Vidhya, Kembro, Jackelyn Melissa, O'Rourke, Brian, Paolocci, Nazareno, Cortassa, Sonia
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362521/
https://ncbi.nlm.nih.gov/pubmed/22585969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210772
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