PRE- AND POST-SYNAPTIC CORTICAL CHOLINERGIC DEFICITS ARE PROPORTIONAL TO AMYLOID PLAQUE PRESENCE AND DENSITY AT PRECLINICAL STAGES OF ALZHEIMER’S DISEASE

Amyloid imaging has identified cognitively normal older people with plaques as a group possibly at increased risk for developing Alzheimer’s disease-related dementia. It is important to begin to thoroughly characterize this group so that preventative therapies might be tested. Existing cholinotropic...

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Detalhes bibliográficos
Main Authors: Potter, Pamela E., Rauschkolb, Paula K., Pandya, Yoga, Sue, Lucia I., Sabbagh, Marwan N., Walker, Douglas G., Beach, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362487/
https://ncbi.nlm.nih.gov/pubmed/21533854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0831-1
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