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Sensitization of breast cancer cells to taxol by inhibition of taxol resistance gene 1

The purpose of this study was to determine the role of taxol resistance gene 1 (TXR1) in a taxol-resistant breast cancer cell line. Expression levels of TXR1 and thrombospondin-1 (TSP1) were detected by RT-PCR and Western blot analysis. In MCF-7 cells transfected with TXR1 plasmids, the expression o...

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Main Authors: BAI, ZHIGANG, ZHANG, ZHONGTAO, QU, XIANG, HAN, WEI, MA, XUEMEI
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362456/
https://ncbi.nlm.nih.gov/pubmed/22740869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.416
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