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Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol
BACKGROUND: Cyclin B1, the regulatory subunit of cyclin-dependent kinase 1 (Cdk1), is essential for the transition from G2 phase to mitosis. Cyclin B1 is very often found to be overexpressed in primary breast and cervical cancer cells as well as in cancer cell lines. Its expression is correlated wit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2639606/ https://ncbi.nlm.nih.gov/pubmed/19113992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-391 |
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